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GANT-61 treatment to RMS cells inhibits proliferation, colony formation...  | Download Scientific Diagram
GANT-61 treatment to RMS cells inhibits proliferation, colony formation... | Download Scientific Diagram

Full article: Chemical, computational and functional insights into the  chemical stability of the Hedgehog pathway inhibitor GANT61
Full article: Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

Inhibition of GLI-mediated transcription and tumor cell growth by  small-molecule antagonists | PNAS
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists | PNAS

GANT 61, GLI1 and 2 inhibitor (CAS 500579-04-4) (ab120904) | Abcam
GANT 61, GLI1 and 2 inhibitor (CAS 500579-04-4) (ab120904) | Abcam

IJMS | Free Full-Text | Widespread Expression of Hedgehog Pathway  Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor  Growth by GANT61: Implications for Cancer Therapy
IJMS | Free Full-Text | Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy

GANT61 | ≥99%(HPLC) | GLI antagonist | AdooQ®
GANT61 | ≥99%(HPLC) | GLI antagonist | AdooQ®

GANT 61 | CAS 500579-04-4 | Cayman Chemical | Biomol.com
GANT 61 | CAS 500579-04-4 | Cayman Chemical | Biomol.com

GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP  III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma |  Cell Death & Disease
GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma | Cell Death & Disease

Expression of GLI1 target genes after GANT61 treatments | Open-i
Expression of GLI1 target genes after GANT61 treatments | Open-i

Molecular mechanism of GANT61 combined with doxorubicin in the treatment of  gliomas based on network pharmacology - ScienceDirect
Molecular mechanism of GANT61 combined with doxorubicin in the treatment of gliomas based on network pharmacology - ScienceDirect

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

GANT61 | ≥99%(HPLC) | GLI antagonist | AdooQ®
GANT61 | ≥99%(HPLC) | GLI antagonist | AdooQ®

GANT-61 Induces Autophagy and Apoptosis in Glioblastoma Cells despite their  heterogeneity | Cellular and Molecular Neurobiology
GANT-61 Induces Autophagy and Apoptosis in Glioblastoma Cells despite their heterogeneity | Cellular and Molecular Neurobiology

Inhibition of autophagy potentiates the efficacy of Gli inhibitor GANT-61  in MYCN-amplified neuroblastoma cells | BMC Cancer | Full Text
Inhibition of autophagy potentiates the efficacy of Gli inhibitor GANT-61 in MYCN-amplified neuroblastoma cells | BMC Cancer | Full Text

APExBIO - GANT61|GLI antagonist |CAS# 500579-04-4
APExBIO - GANT61|GLI antagonist |CAS# 500579-04-4

Down-Regulation of Gli Transcription Factor Leads to the Inhibition of  Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK  Signaling | PLOS ONE
Down-Regulation of Gli Transcription Factor Leads to the Inhibition of Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK Signaling | PLOS ONE

Schematic overview of different GANT61 target sites. Inhibition of the... |  Download Scientific Diagram
Schematic overview of different GANT61 target sites. Inhibition of the... | Download Scientific Diagram

GANT 61 (NSC 136476) | Gli1/2 Inhibitor | MedChemExpress
GANT 61 (NSC 136476) | Gli1/2 Inhibitor | MedChemExpress

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression  and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells
IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells

Schematic representation of the proposed mechanism of GANT61-induced... |  Download Scientific Diagram
Schematic representation of the proposed mechanism of GANT61-induced... | Download Scientific Diagram